Bullous skin eruption associated with carbamazepine overdosage.

Carbamazepine-induced bullous eruption or bullous pemphigoid?

Prevalence of Cutaneous Drug Eruption in Hospitalized Patients: A Report from Sina Hospital of Tabriz

Background: Cutaneous drug reaction seems to be relatively common The aim of the study was to recognize offending drugs, evaluate patients' characteristics and educate the patients to avoid selfadministration and re-administration of drugs. Methods: We retrospectively and prospectively analyzed data from Sina hospital in Tabriz (2000-2005) to determine the number of hospitalizations and visits ...

A Rare Case of Eosinophilic Granulomatosis with Polyangiitis Associated with Cryoglobulinemia Presenting with a Bullous Skin Eruption of the Lower Limbs

Background Eosinophilic granulomatosis with polyangiitis (EGPA) is an antineutrophil cytoplasmic antibody- (ANCA-) associated small vessel vasculitis with multisystem involvement. It is characterized with asthma, eosinophilia, and renal and peripheral nervous system involvement. However, EGPA presenting with bullous skin eruption is an uncommon dermatological manifestation. We report a rare cas...

Characterization of cellular infiltration in polymorphic eruption of pregnancy and pemphigoid gestationis in histopathological examinations

Background: Pregnancy-specific dermatoses represent a group of pruritic skin diseases unique to pregnancy and the most common types are polymorphic eruption of pregnancy and pemphigoid gestationis. It is difficult to obtain a histopathological diagnosis for polymorphic eruption of pregnancy and pemphigoid gestationis in the lack of immunofluorescence because of their similar clinical presentati...

Hypersensitivity to antiepileptic drugs in children

Background Aromatic (lamotrigin, carbamazepine, phenobarbital) and non aromatic antiepileptic (valproat, topiramate) drugs are frequently associated with hypersensitivity reactions mainly cutaneous such as maculopapular exanthems and bullous and pustular eruptions on the basis of their clinical, cellular and molecular pathophysiology. They usually occur more than 1 hour after the last drug admi...